Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
Interleukin 2 (IL-2) receptors are expressed on activated T cells and in select T-cell leukemias. Recently, it has been demonstrated that at least two classes of receptor for IL-2 exist with markedly different affinities for ligand. All known biological actions of IL-2 have been correlated with occu...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1986
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323096/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3081898/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1463 |
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