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The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.

There are at least two interleukin 2 (IL-2) binding peptides: one is the Mr 55,000 peptide (p55) reactive with the anti-Tac monoclonal antibody, and the other is a Mr 75,000 non-Tac IL-2 binding peptide (p75). Independently existing Tac or p75 peptides represent low-affinity IL-2 receptors, whereas...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tsudo, M, Goldman, C K, Bongiovanni, K F, Chan, W C, Winton, E F, Yagita, M, Grimm, E A, Waldmann, T A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298862/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.15.5394
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