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Structural basis for myopathic defects engendered by alterations in the myosin rod
While mutations in the myosin S1 motor domain can directly disrupt the generation and transmission of force along myofibrils and lead to myopathy, the mechanism whereby mutations in the myosin rod influence mechanical function is less clear. Here, we used a combination of various imaging techniques...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230674/ https://ncbi.nlm.nih.gov/pubmed/22037585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.019 |
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