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Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length

Muscle myosin heavy chain (MHC) rod domains intertwine to form alpha-helical coiled-coil dimers; these subsequently multimerize into thick filaments via electrostatic interactions. The subfragment 2/light meromyosin “hinge” region of the MHC rod, located in the C-terminal third of heavy meromyosin,...

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Detalhes bibliográficos
Main Authors: Suggs, Jennifer A., Cammarato, Anthony, Kronert, William A., Nikkhoy, Massoud, Dambacher, Corey M., Megighian, Aram, Bernstein, Sanford I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965590/
https://ncbi.nlm.nih.gov/pubmed/17316684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.045
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