Oral fondaparinux: use of lipid nanocapsules as nanocarriers and in vivo pharmacokinetic study

Oral anticoagulant therapy could be advanced using lipid-based nanoparticulate systems. This study examined lipid nanocapsules for their oral absorption potential as the first step in developing oral fondaparinux (Fp) novel carriers. Using phase inversion method and cationic surfactants such as hexa...

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Main Authors: Ramadan, Alyaa, Lagarce, Frederic, Tessier-Marteau, Anne, Thomas, Olivier, Legras, Pierre, Macchi, Laurent, Saulnier, Patrick, Benoit, Jean Pierre
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2011
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230563/
https://ncbi.nlm.nih.gov/pubmed/22162653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S25791
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