Praziquantel–lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting

PURPOSE: Lipid nanocapsules (LNCs) have shown potential to increase the bioavailability and efficacy of orally administered drugs. However, their intestinal translocation to distal target sites and their implication in pharmacokinetic (PK)–pharmacodynamic (PD) relationships are yet to be elucidated....

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Amara, Rokaya O, Ramadan, Alyaa A, El-Moslemany, Riham M, Eissa, Maha M, El-Azzouni, Mervat Z, El-Khordagui, Labiba K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084080/
https://ncbi.nlm.nih.gov/pubmed/30122922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S167285
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