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Bisphenol-A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response

Bisphenol-A (BPA) is a nonsteroidal estrogen that is ubiquitous in the environment. The homeobox gene Hoxa10 controls uterine organogenesis, and its expression is affected by in utero BPA exposure. We hypothesized that an epigenetic mechanism underlies BPA-mediated alterations in Hoxa10 expression....

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Detalhes bibliográficos
Main Authors: Bromer, Jason G., Zhou, Yuping, Taylor, Melissa B., Doherty, Leo, Taylor, Hugh S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230522/
https://ncbi.nlm.nih.gov/pubmed/20181937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-140533
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