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SU11248, a selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells

SU11248 is a selective inhibitor of certain protein kinases including VEGFR types 1–3 that are expressed in human breast cancer. The present study determines whether the anti-tumor activity of SU11248 results from the inhibition of angiogenesis, as well as direct anti-proliferation and anti-migratio...

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Detalhes bibliográficos
Main Authors: Young, Emily, Miele, Lucio, Tucker, Kevan B, Huang, Min, Wells, Jeremy, Gu, Jian-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230514/
https://ncbi.nlm.nih.gov/pubmed/20686367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.7.12904
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