EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression

The role of EGCG, a major green tea catechin in breast cancer therapy is poorly understood. The present study tests the hypothesis that EGCG can inhibit the activation of HIF-1α and NFκB, and VEGF expression, thereby suppressing tumor angiogenesis and breast cancer progression. Sixteen eight-wk-old...

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Autori principali: Gu, Jian-Wei, Makey, Kristina L, Tucker, Kevan B, Chinchar, Edmund, Mao, Xiaowen, Pei, Ivy, Thomas, Emily Y, Miele, Lucio
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649947/
https://ncbi.nlm.nih.gov/pubmed/23638734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-5-9
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