Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis

Adrenergic stimulation of adipocytes yields a cAMP signal that activates protein kinase A (PKA). PKA phosphorylates perilipin, a protein localized on the surface of lipid droplets that serves as a gatekeeper to regulate access of lipases converting stored triglycerides to free fatty acids and glycer...

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Detalhes bibliográficos
Main Authors: Pidoux, Guillaume, Witczak, Oliwia, Jarnæss, Elisabeth, Myrvold, Linda, Urlaub, Henning, Stokka, Anne Jorunn, Küntziger, Thomas, Taskén, Kjetil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230380/
https://ncbi.nlm.nih.gov/pubmed/21983901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.365
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