Dual Specificity A-kinase Anchoring Proteins (AKAPs) Contain an Additional Binding Region That Enhances Targeting of Protein Kinase A Type I

A-kinase anchoring proteins (AKAPs) target protein kinase A (PKA) to a variety of subcellular locations. Conventional AKAPs contain a 14-18-amino acid sequence that forms an amphipathic helix that binds with high affinity to the regulatory (R) subunit of PKA type II. More recently, a group of dual s...

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Bibliographische Detailangaben
Hauptverfasser: Jarnæss, Elisabeth, Ruppelt, Anja, Stokka, Anne Jorunn, Lygren, Birgitte, Scott, John D., Taskén, Kjetil
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Mechanisms of Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586281/
https://ncbi.nlm.nih.gov/pubmed/18824551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804807200
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