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High Glucose Induces Mitochondrial Morphology and Metabolic Changes in Retinal Pericytes

PURPOSE. Mitochondrial dysfunction is known to play a role in retinal vascular cell loss, a prominent lesion of diabetic retinopathy. High glucose (HG) has been reported to induce mitochondrial fragmentation and dysfunction in retinal endothelial cells, contributing to apoptosis. In this study, the...

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Detalhes bibliográficos
Main Authors: Trudeau, Kyle, Molina, Anthony J. A., Roy, Sayon
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230288/
https://ncbi.nlm.nih.gov/pubmed/21979999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7934
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