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Animal models in the drug discovery pipeline for Alzheimer's disease

With increasing feasibility of predicting conversion of mild cognitive impairment to dementia based on biomarker profiling, the urgent need for efficacious disease-modifying compounds has become even more critical. Despite intensive research, underlying pathophysiological mechanisms remain insuffici...

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Autori principali: Van Dam, Debby, De Deyn, Peter Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229762/
https://ncbi.nlm.nih.gov/pubmed/21371009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01299.x
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