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Animal models in the drug discovery pipeline for Alzheimer's disease

With increasing feasibility of predicting conversion of mild cognitive impairment to dementia based on biomarker profiling, the urgent need for efficacious disease-modifying compounds has become even more critical. Despite intensive research, underlying pathophysiological mechanisms remain insuffici...

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Hlavní autoři: Van Dam, Debby, De Deyn, Peter Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229762/
https://ncbi.nlm.nih.gov/pubmed/21371009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01299.x
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