IL-4 Deficiency Is Associated with Mechanical Hypersensitivity in Mice

Interleukin-4 (IL-4) is an anti-inflammatory and analgesic cytokine that induces opioid receptor transcription. We investigated IL-4 knockout (ko) mice to characterize their pain behavior before and after chronic constriction injury (CCI) of the sciatic nerve as a model for neuropathic pain. We inve...

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Hauptverfasser: Üçeyler, Nurcan, Topuzoğlu, Tengü, Schießer, Peter, Hahnenkamp, Saskia, Sommer, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229527/
https://ncbi.nlm.nih.gov/pubmed/22164245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028205
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