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Impaired contact hypersensitivity to trinitrochlorobenzene in interleukin-4-deficient mice

We have examined the role of endogenously produced interleukin-4 (IL-4) in the contact hypersensitivity (CH) reaction to the haptene trinitrochlorobenzene (TNCB). The CH reaction was abolished in IL-4 genetically deficient mice (IL-4 KO), when compared to wild-type (wt) mice. The CH reaction was res...

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Detalhes bibliográficos
Main Authors: Dieli, F, Sireci, G, Scirè, E, Salerno, A, Bellavia, A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326896/
https://ncbi.nlm.nih.gov/pubmed/10469236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00844.x
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