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IL-4 Deficiency Is Associated with Mechanical Hypersensitivity in Mice
Interleukin-4 (IL-4) is an anti-inflammatory and analgesic cytokine that induces opioid receptor transcription. We investigated IL-4 knockout (ko) mice to characterize their pain behavior before and after chronic constriction injury (CCI) of the sciatic nerve as a model for neuropathic pain. We inve...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229527/ https://ncbi.nlm.nih.gov/pubmed/22164245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028205 |
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