Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts.

Insulin and insulin-like growth factor type I (IGF-I) stimulate an overlapping spectrum of biological responses in human skin fibroblasts. Although insulin and IGF-I are known to stimulate the incorporation of [3H]thymidine into DNA in these cells, the identity of the receptor(s) that mediates this...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Flier, J S, Usher, P, Moses, A C
פורמט: Artigo
שפה:Inglês
יצא לאור: 1986
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC322924/
https://ncbi.nlm.nih.gov/pubmed/3003744
תגים: הוספת תג
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