The nature of enzyme catalysis in trypsin.
We present a combined quantum/molecular mechanical study of the trypsin-catalyzed hydrolysis of a specific tripeptide substrate, including the entire enzyme in the calculation, as well as 200 H2O molecules. The results illustrate how the enzyme and nearby H2O molecules stabilize the ionic intermedia...
-д хадгалсан:
| -д хэвлэсэн: | Proc Natl Acad Sci U S A |
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| Үндсэн зохиолчид: | , , |
| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
National Academy of Sciences
1986
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| Нөхцлүүд: | |
| Онлайн хандалт: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.649 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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