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Purification of microsomal signal peptidase as a complex.

We report here the purification to near homogeneity of signal peptidase from canine pancreatic microsomes. Purification was monitored using an improved post-translational assay. A 42-fold enrichment over starting membranes was achieved by selective solubilization in nonionic detergent/high-salt buff...

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Autors principals: Evans, E A, Gilmore, R, Blobel, G
Format: Artigo
Idioma:Inglês
Publicat: 1986
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC322907/
https://ncbi.nlm.nih.gov/pubmed/3511473
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