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A poliovirus temperature-sensitive RNA synthesis mutant located in a noncoding region of the genome.
We have constructed an 8-base-pair insertion mutation in the 3' noncoding region of an infectious poliovirus cDNA clone that gives rise to a temperature-sensitive RNA synthesis mutant upon transfection into mammalian cells. The mutated cDNA was used to establish a cell line that releases the mu...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1986
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3003739/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.571 |
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