A poliovirus temperature-sensitive RNA synthesis mutant located in a noncoding region of the genome.
We have constructed an 8-base-pair insertion mutation in the 3' noncoding region of an infectious poliovirus cDNA clone that gives rise to a temperature-sensitive RNA synthesis mutant upon transfection into mammalian cells. The mutated cDNA was used to establish a cell line that releases the mutant...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1986
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3003739/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.571 |
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