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A poliovirus temperature-sensitive RNA synthesis mutant located in a noncoding region of the genome.

We have constructed an 8-base-pair insertion mutation in the 3' noncoding region of an infectious poliovirus cDNA clone that gives rise to a temperature-sensitive RNA synthesis mutant upon transfection into mammalian cells. The mutated cDNA was used to establish a cell line that releases the mu...

詳細記述

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書誌詳細
主要な著者: Sarnow, P, Bernstein, H D, Baltimore, D
フォーマット: Artigo
言語:Inglês
出版事項: 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC322905/
https://ncbi.nlm.nih.gov/pubmed/3003739
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