The role of SMAD4 in early-onset colorectal cancer

OBJECTIVE: Chromosomal loss within the region of 18q and loss of SMAD4 expression have been reported to be frequent somatic events during colorectal cancer tumour progression; however, their associations with age at onset have not been widely studied. METHOD: We analysed 109 tumours from a populatio...

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Autors principals: Royce, S. G., Alsop, K., Haydon, A., Mead, L., Smith, L. D., Tesoriero, A. A., Giles, G. G., Jenkins, M. A., Hopper, J. L., Southey, M. C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228835/
https://ncbi.nlm.nih.gov/pubmed/19183329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1318.2009.01779.x
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