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Infrequent mutation of the tumour-suppressor gene Smad4 in early-stage colorectal cancer

Smad4 is a candidate tumour-suppressor gene identified recently on chromosome 18q21.1. Both alleles are inactivated in nearly one-half of pancreatic carcinomas, but its role in the tumorigenesis of other tumours is still unknown. The aim of this study was to investigate the potential involvement of...

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מידע ביבליוגרפי
Main Authors: Mamot, C, Mild, G, Reuter, J, Laffer, U, Metzger, U, Terracciano, L, Boulay, J-L, Herrmann, R, Rochlitz, C
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747552/
https://ncbi.nlm.nih.gov/pubmed/12569386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600733
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