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Infrequent mutation of the tumour-suppressor gene Smad4 in early-stage colorectal cancer
Smad4 is a candidate tumour-suppressor gene identified recently on chromosome 18q21.1. Both alleles are inactivated in nearly one-half of pancreatic carcinomas, but its role in the tumorigenesis of other tumours is still unknown. The aim of this study was to investigate the potential involvement of...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747552/ https://ncbi.nlm.nih.gov/pubmed/12569386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600733 |
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