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SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer
The gene for the transducer of transforming growth factor-beta/bone morphogenetic protein signalling SMAD4, a potential suppressor of colorectal carcinogenesis, is located at the chromosomal region 18q21. In order to evaluate the clinical relevance of SMAD4 deletion, gene copy alterations were deter...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364238/ https://ncbi.nlm.nih.gov/pubmed/12237773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600511 |
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