SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer

The gene for the transducer of transforming growth factor-beta/bone morphogenetic protein signalling SMAD4, a potential suppressor of colorectal carcinogenesis, is located at the chromosomal region 18q21. In order to evaluate the clinical relevance of SMAD4 deletion, gene copy alterations were deter...

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Detalhes bibliográficos
Main Authors: Boulay, J-L, Mild, G, Lowy, A, Reuter, J, Lagrange, M, Terracciano, L, Laffer, U, Herrmann, R, Rochlitz, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Molecular and Cellular Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364238/
https://ncbi.nlm.nih.gov/pubmed/12237773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600511
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