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Identification of a Genomic Reservoir for New TRIM Genes in Primate Genomes

Tripartite Motif (TRIM) ubiquitin ligases act in the innate immune response against viruses. One of the best characterized members of this family, TRIM5α, serves as a potent retroviral restriction factor with activity against HIV. Here, we characterize what are likely to be the youngest TRIM genes i...

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Detalhes bibliográficos
Main Authors: Han, Kyudong, Lou, Dianne I., Sawyer, Sara L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228819/
https://ncbi.nlm.nih.gov/pubmed/22144910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002388
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