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Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma.

Amplified cellular genes are frequently manifested in one of two cytologically recognizable forms, double minutes or homogeneously staining regions. Additionally, evidence is accumulating that aberrant expression of cellular genes (including oncogenes) may be mediated by gene amplification. We now d...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Trent, J, Meltzer, P, Rosenblum, M, Harsh, G, Kinzler, K, Mashal, R, Feinberg, A, Vogelstein, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322881/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3001737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.470
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