Isolation and structural analysis of a 1.2-megabase N-myc amplicon from a human neuroblastoma.

Oncogene amplification is observed frequently in human cancers, but little is known about the mechanism of gene amplification or the structure of amplified DNA in tumor cells. We have studied the N-myc amplified domain from a representative neuroblastoma cell line, SMS-KAN, and compared the map of t...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Schneider, S S, Hiemstra, J L, Zehnbauer, B A, Taillon-Miller, P, Le Paslier, D L, Vogelstein, B, Brodeur, G M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1448086/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.12.5563-5570.1992
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