Isolation and structural analysis of a 1.2-megabase N-myc amplicon from a human neuroblastoma.

Oncogene amplification is observed frequently in human cancers, but little is known about the mechanism of gene amplification or the structure of amplified DNA in tumor cells. We have studied the N-myc amplified domain from a representative neuroblastoma cell line, SMS-KAN, and compared the map of t...

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Bibliographic Details
Main Authors: Schneider, S S, Hiemstra, J L, Zehnbauer, B A, Taillon-Miller, P, Le Paslier, D L, Vogelstein, B, Brodeur, G M
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC360495/
https://ncbi.nlm.nih.gov/pubmed/1448086
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