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Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity
BACKGROUND: Acetaminophen (APAP) overdose induces massive hepatocyte necrosis. Liver regeneration is a vital process for survival after a toxic insult. Since hepatocytes are mostly in a quiescent state (G(0)), the regeneration process requires the priming of hepatocytes by cytokines such as TNF-α an...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228804/ https://ncbi.nlm.nih.gov/pubmed/22085740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-125 |
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