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Runx1 Loss Minimally Impacts Long-Term Hematopoietic Stem Cells
RUNX1 encodes a DNA binding subunit of the core-binding transcription factors and is frequently mutated in acute leukemia, therapy-related leukemia, myelodysplastic syndrome, and chronic myelomonocytic leukemia. Mutations in RUNX1 are thought to confer upon hematopoietic stem cells (HSCs) a pre-leuk...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228772/ https://ncbi.nlm.nih.gov/pubmed/22145044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028430 |
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