β(7) Integrin Deficiency Suppresses B Cell Homing and Attenuates Chronic Ileitis in SAMP1/YitFc Mice

Lymphocyte recruitment to intestinal tissues depends on β(7) integrins. In this study, we studied disease severity and lymphocyte recruitment into the small intestine in SAMP1/YitFc mice, which develop chronic ileitis with similarity to human Crohn’s disease. To assess the role of β(7) integrins in...

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Main Authors: Gorfu, Gezahegn, Rivera-Nieves, Jesus, Hoang, Sharon, Abbott, Derek W., Arbenz-Smith, Keely, Azar, David W., Pizarro, Theresa T., Cominelli, Fabio, McDuffie, Marcia, Ley, Klaus
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228636/
https://ncbi.nlm.nih.gov/pubmed/20926792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903938
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