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Introduction of genes into preimplantation mouse embryos by use of a defective recombinant retrovirus.

Two-cell and four-cell preimplantation mouse embryos were cocultured in vitro with fibroblasts producing the recombinant retrovirus M-MuLV-neo. No wildtype helper virus was detected in these cultures. Of the embryos that survived the in vitro cultivation and the reimplantation into foster mothers, 2...

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Hlavní autoři: Rubenstein, J L, Nicolas, J F, Jacob, F
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC322859/
https://ncbi.nlm.nih.gov/pubmed/3455774
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