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Construction of a retrovirus capable of transducing and expressing genes in multipotential embryonic cells.

Retroviral gene expression is inhibited in embryonal carcinoma (EC) cells. We have constructed a recombinant retroviral vector that is capable of expressing the neomycin-resistance (neo) gene in EC cells. The critical modification that permits expression of the neo gene is the insertion of a composi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rubenstein, J L, Nicolas, J F, Jacob, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC392092/
https://ncbi.nlm.nih.gov/pubmed/6095270
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