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Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells.
The mechanism by which mammalian cells acquire resistance to chemotherapeutic agents has been investigated by using molecular genetic techniques. LZ and C5, two independently derived multidrug-resistant Chinese hamster cell lines, share specific amplified DNA sequences. We demonstrate that commonly...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3455770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.337 |
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