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Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells.

The mechanism by which mammalian cells acquire resistance to chemotherapeutic agents has been investigated by using molecular genetic techniques. LZ and C5, two independently derived multidrug-resistant Chinese hamster cell lines, share specific amplified DNA sequences. We demonstrate that commonly...

詳細記述

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書誌詳細
主要な著者: Gros, P, Croop, J, Roninson, I, Varshavsky, A, Housman, D E
フォーマット: Artigo
言語:Inglês
出版事項: 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC322853/
https://ncbi.nlm.nih.gov/pubmed/3455770
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