Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells.

The mechanism by which mammalian cells acquire resistance to chemotherapeutic agents has been investigated by using molecular genetic techniques. LZ and C5, two independently derived multidrug-resistant Chinese hamster cell lines, share specific amplified DNA sequences. We demonstrate that commonly...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Gros, P, Croop, J, Roninson, I, Varshavsky, A, Housman, D E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3455770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.337
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