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Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors
Persistent relapse to addictive drugs constitutes the most challenging problem in addiction therapy, and is linked to impaired prefrontal cortex regulation of motivated behaviors involving the nucleus accumbens. Using a rat model of heroin addiction, we show that relapse requires long-term potentiat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228456/ https://ncbi.nlm.nih.gov/pubmed/22084102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112052108 |
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