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Reduced LTP and LTD in Prefrontal Cortex Synapses in the Nucleus Accumbens After Heroin Self-Administration

Addiction changes prefrontal cortex regulation of the nucleus accumbens, including reduced ability to induce long-term potentiation (LTP) and long-term depression (LTD). This important potential mechanism of impaired prefrontal regulation of behavior has been shown only for cocaine. Here we show tha...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Shen, Haowei, Kalivas, Peter W
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349426/
https://ncbi.nlm.nih.gov/pubmed/23110855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145712001071
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