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Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking

BACKGROUND: Opioid addiction is a critical medical and social problem characterized by vulnerability to relapse. Glutamatergic synapses in the nucleus accumbens regulate the motivation to relapse to opioid use and down-regulation of glutamate transporters on astroglial processes adjacent to accumben...

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Bibliographic Details
Published in:Biol Psychiatry
Main Authors: Kruyer, Anna, Scofield, Michael D., Wood, Daniel, Reissner, Kathryn J., Kalivas, Peter W.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823145/
https://ncbi.nlm.nih.gov/pubmed/31495448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.06.026
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