Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system

Unlike the dominant role of one class II invariant chain peptide (CLIP) in blocking MHC class II, comparative lipidomics analysis shows that human cluster of differentiation (CD) proteins CD1a, CD1b, CD1c, and CD1d bind lipids corresponding to hundreds of diverse accurate mass retention time values....

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Detalhes bibliográficos
Main Authors: Huang, Shouxiong, Cheng, Tan-Yun, Young, David C., Layre, Emilie, Madigan, Cressida A., Shires, John, Cerundolo, Vincenzo, Altman, John D., Moody, D. Branch
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228429/
https://ncbi.nlm.nih.gov/pubmed/22087000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112969108
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