Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system

Unlike the dominant role of one class II invariant chain peptide (CLIP) in blocking MHC class II, comparative lipidomics analysis shows that human cluster of differentiation (CD) proteins CD1a, CD1b, CD1c, and CD1d bind lipids corresponding to hundreds of diverse accurate mass retention time values....

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Bibliographic Details
Main Authors: Huang, Shouxiong, Cheng, Tan-Yun, Young, David C., Layre, Emilie, Madigan, Cressida A., Shires, John, Cerundolo, Vincenzo, Altman, John D., Moody, D. Branch
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228429/
https://ncbi.nlm.nih.gov/pubmed/22087000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112969108
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