Nalaganje...
Basic residues in the T-cell receptor ζ cytoplasmic domain mediate membrane association and modulate signaling
The T-cell receptor (TCR) consists of a TCRαβ heterodimer, a TCRζ homodimer, and CD3γε and CD3δε heterodimers. The precise mechanism of T-cell triggering following TCR ligand engagement remains elusive. Previous studies reported that the cytoplasmic tail of CD3ε binds to the plasma membrane through...
Shranjeno v:
| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228420/ https://ncbi.nlm.nih.gov/pubmed/22084078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108052108 |
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