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Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I.

The mechanism of the idling-turnover reaction catalyzed by the large (Klenow) fragment of Escherichia coli DNA polymerase I has been investigated. The reaction cycle involved is one of excision/incorporation, in which the 3' deoxynucleotide residue of the primer DNA strand is partitioned into its 5'...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Mizrahi, V, Benkovic, P A, Benkovic, S J
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3510431/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.231
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