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Nonsense-mediated Decay of mRNA for the Selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase Is Detectable in Cultured Cells but Masked or Inhibited in Rat Tissues

Previous studies of mRNA for classical glutathione peroxidase 1 (GPx1) demonstrated that hepatocytes of rats fed a selenium-deficient diet have less cytoplasmic GPx1 mRNA than hepatocytes of rats fed a selenium-adequate diet. This is because GPx1 mRNA is degraded by the surveillance pathway called n...

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Autors principals: Sun, Xiaolei, Li, Xiaojie, Moriarty, Patrick M., Henics, Tamás, LaDuca, Jeffrey P., Maquat, Lynne E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC32283/
https://ncbi.nlm.nih.gov/pubmed/11294903
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