Sublingual Immunization with M2-Based Vaccine Induces Broad Protective Immunity against Influenza

BACKGROUND: The ectodomain of matrix protein 2 (M2e) of influenza A virus is a rationale target antigen candidate for the development of a universal vaccine against influenza as M2e undergoes little sequence variation amongst human influenza A strains. Vaccine-induced M2e-specific antibodies (Abs) h...

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Main Authors: Shim, Byoung-Shik, Choi, Young Ki, Yun, Cheol-Heui, Lee, Eu-Gene, Jeon, Yoon Seong, Park, Sung-Moo, Cheon, In Su, Joo, Dong-Hyun, Cho, Chung Hwan, Song, Min-Suk, Seo, Sang-Uk, Byun, Young-Ho, Park, Hae-Jung, Poo, Haryoung, Seong, Baik Lin, Kim, Jae Ouk, Nguyen, Huan Huu, Stadler, Konrad, Kim, Dong Wook, Hong, Kee-Jong, Czerkinsky, Cecil, Song, Man Ki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227615/
https://ncbi.nlm.nih.gov/pubmed/22140491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027953
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