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A Transmembrane Form of the Prion Protein Contains an Uncleaved Signal Peptide and Is Retained in the Endoplasmic Reticululm

Although there is considerable evidence that PrP(Sc) is the infectious form of the prion protein, it has recently been proposed that a transmembrane variant called (Ctm)PrP is the direct cause of prion-associated neurodegeneration. We report here, using a mutant form of PrP that is synthesized exclu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stewart, Richard S., Drisaldi, Bettina, Harris, David A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC32273/
https://ncbi.nlm.nih.gov/pubmed/11294893
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