Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

Visceral leishmaniasis is a potentially fatal disease endemic to large parts of Asia and Africa, primarily caused by the protozoan parasite Leishmania donovani. Here, we report a high-quality reference genome sequence for a strain of L. donovani from Nepal, and use this sequence to study variation i...

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Detalhes bibliográficos
Main Authors: Downing, Tim, Imamura, Hideo, Decuypere, Saskia, Clark, Taane G., Coombs, Graham H., Cotton, James A., Hilley, James D., de Doncker, Simonne, Maes, Ilse, Mottram, Jeremy C., Quail, Mike A., Rijal, Suman, Sanders, Mandy, Schönian, Gabriele, Stark, Olivia, Sundar, Shyam, Vanaerschot, Manu, Hertz-Fowler, Christiane, Dujardin, Jean-Claude, Berriman, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227103/
https://ncbi.nlm.nih.gov/pubmed/22038251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.123430.111
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