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Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level

Here, we report a pilot study paving the way for further single cell genomics studies in Leishmania. First, the performances of two commercially available kits for Whole Genome Amplification (WGA), PicoPLEX and RepliG were compared on small amounts of Leishmania donovani DNA, testing their ability t...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Imamura, Hideo, Monsieurs, Pieter, Jara, Marlene, Sanders, Mandy, Maes, Ilse, Vanaerschot, Manu, Berriman, Matthew, Cotton, James A., Dujardin, Jean-Claude, Domagalska, Malgorzata A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490275/
https://ncbi.nlm.nih.gov/pubmed/32929126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71882-2
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